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Concept

The goal of the lMIDIA project is to develop novel approaches to assess, predict and prevent pancreatic beta-cell demise as well as to restore normal beta-cell mass and function for the treatment of Diabetes patients.

The scientific programme of the IMIDIA consortium aims at delivering:

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Novel tools for the study of human pancreatic beta-cell development, function and survival, their modulation by potential therapeutic compounds and for in vivo beta-cell imaging

Biomarker for diagnosis and prognosis of beta-cell failure and for monitoring diabetes progression and success of disease treatment

Knowledge on novel pathways and sites that control beta-cell proliferation, differentiation and apoptosis, and on the role of nutrient-regulated pathways and sites in controlling beta-cell mass and function