The goal of the lMIDIA project is to develop novel approaches to assess, predict and prevent pancreatic beta-cell demise as well as to restore normal beta-cell mass and function for the treatment of Diabetes patients.
The scientific programme of the IMIDIA consortium aims at delivering:
Novel tools for the study of human pancreatic beta-cell development, function and survival, their modulation by potential therapeutic compounds and for in vivo beta-cell imaging
Biomarker for diagnosis and prognosis of beta-cell failure and for monitoring diabetes progression and success of disease treatment
Knowledge on novel pathways and sites that control beta-cell proliferation, differentiation and apoptosis, and on the role of nutrient-regulated pathways and sites in controlling beta-cell mass and function